0What are the signs of Cushing's disease in dogs?
Excessive drinking and urination (2-3x normal, including overnight). Increased appetite, pot-bellied appearance, bilateral hair loss, thin fragile skin, recurring infections, excessive panting. Many owners mistake these for normal aging.
1How much does Cushing's disease treatment cost?
First year: $2,000-$5,000 - diagnostics ($500-$1,500), Trilostane ($50-$200/month), and 4-6 ACTH tests ($200-$400 each). Subsequent years: $1,500-$4,000 with medication and monitoring every 3-6 months. Adrenal surgery: $2,000-$5,000 if needed.
2How is Cushing's disease diagnosed?
Blood work shows elevated ALP and cholesterol. ACTH stimulation or low-dose dexamethasone suppression confirms abnormal cortisol. Ultrasound evaluates adrenals - bilateral enlargement suggests pituitary-dependent; single enlarged gland suggests adrenal tumor. Total: $500-$1,500.
3Can Cushing's disease be cured?
Pituitary-dependent (85%) cannot be cured - managed with daily Trilostane for life. Adrenal-dependent (15%) may be cured by surgical tumor removal but carries risk. Iatrogenic Cushing's resolves when steroids taper. Managed dogs live well.
4What is the life expectancy for a dog with Cushing's disease?
With treatment, pituitary-dependent dogs typically live 2-3 years post-diagnosis, often longer. Since most are 8+ at diagnosis, lifespan isn't dramatically shortened. Untreated, progressive complications significantly reduce quality and length of life.
5What is Trilostane and what are the side effects?
Trilostane (Vetoryl) blocks cortisol production in adrenal glands - standard treatment for both types. Side effects: decreased appetite, vomiting, diarrhea, lethargy, weakness. Serious risk: Addisonian crisis (cortisol drops too low, causing collapse or death). Regular ACTH tests are essential.
6What breeds are most prone to Cushing's disease?
Poodles (all sizes), Dachshunds, Beagles, Boxers, Boston Terriers, and Yorkies have highest incidence. More common in small to medium breeds. Most affected dogs are over 8 years old. Any senior dog with excessive drinking and pot belly should be tested.
7Does pet insurance cover Cushing's disease?
Most policies cover Cushing's as a standard illness. At $2,000-$5,000 year one and $1,500-$4,000/year after, it's highly impactful. Enroll before signs appear in vet records. Once diagnosed, it's pre-existing for any new policy.